New Sources for Drug discovery-Really astonishing’-
Eptifibatide is a cyclic heptapeptide derived from a protein found in the
venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the so-called arginin-glycin-aspartat-mimetics
and reversibly binds to platelets. Integrilin®
is sold in two strengths, globally: vials containing 2 mg/ml (20 mg
totally) and 0.75 mg/ml (75 mg totally). A third size is sold in the
US: 100 ml vials containing 2 mg/ml (200 mg totally). Eptifibatide is
a cyclic heptapeptide containing 6 amino acids and 1 mercaptopropionyl
(des-amino cysteinyl) residue. Each 10-mL vial contains 2 mg/mL of INTEGRILIN
and each 100-mL vial contains either 0.75 mg/mL of INTEGRILIN or 2 mg/mL of
INTEGRILIN.
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